What is gene editing?

Female scientists Emmanuel Sharpji and Jennifer Doudna have received Nobel Prizes in chemistry for the year 2020. These scientists have developed the CAS-9 (Crisper - Cas-9) method for genome editing, i.e., DNA structure changes. This genus addition technique has been named 'genetic caesars,' i.e., 'molecule - scissors.' If a researcher wants to know and change humans' inner workings, animals, plants, and microorganisms, this is not possible without a molecule - scissors. Using this technique, China has brought clones of two girls, two mice, and monkeys into existence in 2018 itself.

The use of hereditary additions and embryonic column cells inspired the Ved Vyasa Mahabharata. Balakrishnan Ganpatrao Matapurkar has also been done in the US laboratory. The US has also given them intellectual rights to this experiment in 1996. Matapurakar wrote the first article on this in 1991, in which he mentioned the formation of organs inside the body. Gene editing is a technique through which the possibilities of producing the desired offspring have increased in the future. Dr. Matapurakar has a degree in Surgeon from GR Medical College, Gwalior. They admit that 'I have not innovated anything, our ancestors have done many such experiments in ancient times, whose sources are found in Mahabharata and other texts.

Satyavati was the daughter of King Gadhi and the wife of sage Ritchie. When Satyavati had no children, the sage Bhrigu took measures to produce children artificially. At the same time, Satyavati pleaded with Bhrigu that he has no brother, so his mother should also take steps to be born as a child. Then Bhrigu prepared two charu (pitches) containing various medicines. Of these, Satyavati's mother was designed to be a son endowed with Kshatriya qualities and created the sutras - the virtues of being an even son for Satyavati. When childbirth came closer, he took medicine prescribed for daughter Satyavati herself and fed Satyavati a cure for her. As a result, Jamadagni was born from Satyavati's womb, and Vishwamitra was taken from her mother's womb. Later, Parshuram was born from these Jamadagni.

 The second episode is that of Dhritarashtra's wife, Gandhari, the mother of the Kauravas. When Gandhari became pregnant, she had an abortion before the completion of nine months. Maharishi Vyas completed the method of the birth of hundred sons from a body of flesh. If Gandhari desired a daughter, Vyas came back and made some radical changes in a fraction. At the end of the stipulated period, a son was born to 99 pots and a daughter from a bank, named Dushala. These measures are in line with gene editing and cloning methods.

Genome editing is a way of making changes to specific parts of a genome. Scientists have been able to alter DNA since the 1970s, but in recent years, they have developed faster, cheaper, and more precise methods to add, remove, or change genes in living organisms.

What Is ZFN Technology?

Zinc finger nucleases (ZFNs) are a class of engineered DNA-binding proteins that facilitated targeted editing of the genome by creating double-strand breaks in DNA at user-specified locations.

Zinc-finger nucleases (ZFNs) are targetable DNA cleavage reagents that have been adopted as gene-targeting tools. ZFN-induced double-strand breaks are subject to cellular DNA repair processes that lead to both targeted mutagenesis and targeted gene replacement at remarkably high frequencies.

CRISPR / Cas9 edits genes by precisely cutting DNA and letting natural DNA repair processes take over. The system consists of two parts: the Cas9 enzyme and a guide RNA. They are rapidly translating revolutionary technology into transformative therapies.

A: "CRISPR" (pronounced "crisper") stands for Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system that forms the basis for CRISPR-Cas9 genome editing technology.