Anti-chemical cheminformatic search or natural of drugs HOO-IMM PLUS (A, B, C, D, E)
CERTIFICATE
The use of a natural medicinal plant to treat HIV / AIDS has recently gained public interest, with extensive research into ethnomedicine worldwide. Although no drugs have been licensed to date, this policy remains controversial in many lands. Plants and other natural products present a great record of the breakdown of active chemicals. In this research project, with HOOIMM PLUS (A, B, C, D, E),
the anti-virus herb-drug produced by HOOTONE REMEDIES, contains 33 different plant species found in India, found to have anti-HIV active chemicals including -diterpenes, triterpenes, biflavonoids, coumarins, gallotannins, galloylquinic acids, curcumins and limonoids etc. antimicrobial activity. These active compounds prevent various stages in the life cycle HIV. The main objective of this study was to conduct a database of plant literature and their natural anti-inflammatory products - HIV an active compound available in HOOIMM plus. Such Bioinformatic database research is an important requirement and a starting point in the search for new treatments for HIV / AIDS from natural plants.
INTRODUCTION
Natural products remain a major source of new medicines. Recent data show that 80% of drug molecules are natural products or natural compounds. A study on the source of new medicines from 1981 to 2014 revealed that about half of the drugs approved since 1994 are derived from natural products. Indian natural products have contributed to this “explosion” in drug discovery.
The process of finding drugs in a plant, however, is troublesome and time consuming. This research article focuses on the process of working hard and taking time. This research article focuses on the role of natural plants in the treatment of HIV / AIDS and opportunistic infections.
The standard recovery process aims to identify a single, pure active ingredient from the active extract and how to balance it in the raw material. An ancient example of the discovery of drugs such as morphine, quinine, digoxin, etc. which replaced their plant extracts in particular was responsible for maintaining the notion that a single active ingredient should be responsible for its action.
The downside to this concept is that you don’t look at the interactions or conflicting features that exist in the segment. Apart from this some parts may also have various other functions. This feature is confirmed by a few examples reported in the literature where the provided work of fragmentary compounds can not be compared with that of pure individual compounds.
Most of the new work in medical plants is especially the detection of long-known effects at cell and cellular levels. The uncertainty of previous studies is evident in the case of biological work due to the lack of a standard posture or example where even if they were in the old state.
Natural herbal medicine has a very long history of use in many diseases and disorders, however, which is a major pillar of action and mechanism of action is not yet clear. More recently, however, it has been suggested that drug availability should not always be limited to the acquisition of a single molecule and the current belief that a “single path for single disease”
May not be tolerated in the future and that a well-planned polyherbal formation can also be investigated The development of established, safe and effective remedies with proven scientific evidence can also provide an alternative to savings in a number of disease areas. However some pro's and cons need attention in the development of natural medicine.
AIDS-related diseases remain a major cause of death worldwide. According to UNAIDS, the number of people living with HIV / AIDS worldwide is estimated at 35 million. Current antiretroviral drugs have many side effects including resistance, toxicity, limited availability, high cost and lack of any treatment (Vermani and Garg, 2002). These shortcomings of standard ART continue to open up new areas for the use of ethnomedicinal plants and other natural products for the management of HIV / AIDS.
In many countries, the inclusion of anti-HIV ethnomedicines and other natural products in the official policy of HIV / AIDS is a serious and controversial issue. It is sensitive because anti - HIV ethnomedicines and other natural products can turn into a goat of rejection and inertia of taking ART.
It is also controversial because in various resource-poor areas, government-funded ART programs do not promote the use of traditional medicine, fearing that the effectiveness of antiretroviral drugs may be hindered by such natural products, or that their chemical interactions could lead to toxicity.
Reliance on anti-HIV and other natural products can also lead to adverse adherence to ART (Langlois-Klassen et al., 2007). Therefore, many governments still have conflicting views on the use of anti-HIV and other natural products in the management of HIV / AIDS, discourage them from ART programs, and support them in other public health and primary health care programs.
By early 1989, the World Health Organization (WHO) had already indicated the need to test ethnomedicines and other natural products for the management of HIV / AIDS:
“In this case, there is a need to test those components of traditional medicine, especially medicinal plants and other products. natural resources that may produce effective and affordable medical devices. This will require a systematic approach ”, says the WHO memorandum (1989).
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